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EPA Overlooks Glyphosate and Roundup Ingredients’ Cancer, DNA Damage, and Multigenerational Effects

EPA Overlooks Glyphosate and Roundup Ingredients’ Cancer, DNA Damage, and Multigenerational Effects
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From Beyond Pesticides

Glyphosate and glyphosate-based herbicides (GBH) like Roundup® induce DNA damage and alter biological mechanisms (gene regulatory microRNAs [miRNAs or miRs]) associated with cancer development. According to the study published in Toxicological Sciences, DNA damage mainly occurs through oxidative stress from GBH exposure. Moreover, DNA damage and other biological mechanisms that cause carcinogenicity (cancer) occur at doses assumed “safe” by pesticide regulators such as the U.S. Environmental Protection Agency (EPA).

Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm

Almost five decades of extensive glyphosate-based herbicide use has put human, animal, and environmental health at risk. The chemical’s ubiquity threatens 93 percent of all U.S. endangered species, resulting in biodiversity loss and ecosystem disruption (e.g., soil erosionloss of services). Exposure to GBHs has implications for specific alterations in microbial gut composition and trophic cascades. Similar to this paper, past studies find a strong association between glyphosate exposure and the development of various health anomalies, including cancerParkinson’s disease, and autism. Although EPA classifies glyphosate herbicides as “not likely to be carcinogenic to humans,” stark evidence demonstrates links to various cancers, including non-Hodgkin lymphoma. Thus, EPA’s classification perpetuates environmental injustice among individuals disproportionately exposed to chemicals like farmworkers, especially in marginalized communities.  Chemical companies knowingly failed and continue to fail to warn farmers adequately about the dangers of the pesticide, and that the manufacturer’s (Bayer/Monsanto) chemical review conclusions are supported by accurate science.

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