• Home
Latest Natural Health News

Vitamin D and the Flu: More about the Science

25. Karatekin G, Kaya A, Salihoğlu O, Balci H, Nuhoğlu A. Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers. Eur J Clin Nutr. 2009 Apr;63(4):473-7.

26. Cannell JJ, Vieth R, Umhau JC, et al. Epidemic influenza and vitamin D. Epidemiol Infect. 2006 Dec;134(6):1129-40.

27. Alvarez-Díaz S, Valle N, García JM, et al. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. J Clin Invest. 2009 Aug;119(8):2343-58.

28. Lowe L, Hansen CM, Senaratne S, Colston KW. Mechanisms implicated in the growth regulatory effects of vitamin d compounds in breast cancer cells. Recent Results Cancer Res. 2003 164:99-110.

29. Moreno J, Krishnan AV, Peehl DM, Feldman D. Mechanisms of vitamin D-mediated growth inhibition in prostate cancer cells: inhibition of the prostaglandin pathway. Anticancer Res. 2006 Jul;26(4A):2525-30.

30. Lehmann B. The vitamin D3 pathway in human skin and its role for regulation of biological processes. Photochem Photobiol. 2005 Nov-Dec;81(6):1246-51.

31. Qiao G, Kong J, Uskokovic M, Li YC. Analogs of 1alpha,25-dihydroxyvitamin D(3) as novel inhibitors of renin biosynthesis. J Steroid Biochem Mol Biol. 2005 Jun;96(1):59-66.

32. Johansson S. Vitamin A and Osteoporosis: Experimental and Clinical Studies. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine. Uppsala University, Sweden. 2004 pg. 1392.

33. Rohde CM, DeLuca HF. All-trans retinoic acid antagonizes the action of calciferol and its active metabolite, 1,25-dihydroxycholecalciferol, in rats. J Nutr. 2005 Jul;135(7):1647-52

34. Rohde CM, Manatt, Clagett-Dame M, DeLuca HF. Vitamin A antagonizes the action of vitamin D in rats. J Nutr. 1999 Dec;129(12):2246-50.

35. Termorshuizen F, Wijga A, Gerritsen J, Neijens HJ, van Loveren H. Exposure to solar ultraviolet radiation and respiratory tract symptoms in 1-year-old children. Photodermatol Photoimmunol Photomed. 2004 Oct;20(5):270-1.

36. Wayse V, Yousafzai A, Mogale K, Filteau S. Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. Eur J Clin Nutr. 2004 Apr;58(4):563-7.

37. Cannell JJ, Zasloff M, Garland CF, Scragg R, Giovannucci E. On the epidemiology of influenza. Virol J 2008 5:29.

Available at: http://www.virologyj.com/content/pdf/1743-422X-5-29.pdf. Accessed September 29, 2009.

38. Available at: http://www.cdc.gov/flu/about/disease/us_flu-related_deaths.htm. Accessed October 7, 2009.

39. Peterson CA, Heffernan ME. Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women. J Inflamm (Lond). 2008 Jul 24;5:10.

40. Van der Meide PH, Schellekens H. Cytokines and the immune response. Biotherapy. 1996 8(3-4):243-9.

41. Devaux B, Scholz D, Hirche A, Klövekorn WP, Schaper J. Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure. Eur Heart J. 1997 Mar;18(3):470-9.

42. Licinio J, Wong ML. The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection. Mol Psychiatry. 1999 Jul;4(4):317-27.

43. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. NEJM. 1997 Apr 3;336(14):973-9.

44. De Keyser F, Elewaut D, De Vos M, et al. Bowel inflammation and the spondyloarthropathies. Rheum Dis Clin North Am. 1998 Nov;24(4):785-813, ix-x.

45. Schauber J, Dorschner RA, Coda AB, et al. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest. 2007 Mar;117(3):803-11.

46. Aloia JF, Patel M, Dimaano R, et al. Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration. Am J Clin Nutr. 2008 Jun;87(6):1952-8.

47. Dawson-Hughes B, Heaney RP, Holick MF, Lips P, Meunier PJ, Vieth R. Estimates of optimal vitamin D status. Osteoporos Int. 2005 Jul;16(7):713-6.

48. Heaney RP, Armas LA, Shary JR, Bell NH, Binkley N, Hollis BW. 25-Hydroxylation of vitamin D3: relation to circulating vitamin D3 under various input conditions. Am J Clin Nutr. 2008 Jun;87(6):1738-42.

49. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am.J Clin Nutr. 1999 May;69(5):842-56.

50. Holick MF. The role of vitamin D for bone health and fracture prevention. Curr Osteoporos Rep. 2006 Sep;4(3):96-102.

51. Tukaj C. [Adequate level of vitamin D is essential for maintaining good health]. Postepy Hig Med Dosw. 2008 Oct 9;62:502-10.

52. Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc. 2006 Mar;81(3):353-73. Available at: http://www.grc.com/health/pdf/High_Prevalence_of_Vitamin_D_Inadequacy_and_Implications_for_Health.pdf. Accessed October 5, 2009.

53. Hanley DA, Davison KS. Vitamin D insufficiency in North America. J Nutr. 2005 Feb;135(2):332-7. Available at: http://jn.nutrition.org/cgi/content/full/135/2/332. Accessed October 5, 2009.

54. Yetley EA. Assessing the vitamin D status of the US population. Am J Clin Nutr. 2008 Aug;88(2):558S-564S.

55. Looker AC, Pfeiffer CM, Lacher DA, Schleicher RL, Picciano MF, Yetley EA. Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004. Am J Clin Nutr. 2008 Dec;88(6):1519-27.

56. Ginde AA, Liu MC, Camargo CA Jr. Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004. Arch Intern Med. 2009 Mar 23;169(6):626-32.

Share This Post

24 thoughts on “Vitamin D and the Flu: More about the Science

  • […] Vitamin D and the Flu: More about the Science Bill Faloon, Co-founder of Life Extension Foundation, recently summarized some of the science showing the critical role of Vitamin D in preventing and controlling infections due to the flu. An excerpt from his article in the January 2010 Life Extension Magazine follows: Click here to learn more » […]

  • Shiu Hung

    No forced vaccinations. We need genuine health care reform with a Single Payer system, not punitive mandates that will generate tremendous profits for insurance & pharmaceutical monopolies.

    • Mike in MI

      Mr. SHIU – –
      Why do you think BOMB’R’CARE is a feint, intermediate step, “statue of liberty” play of the OBOMBer Admin to get us moving to Single Payer? They want this to ultimately cede to the traditional allopathic community, Pharma/Food Chemical Industries (via FDA oversight and regulation) and national disease production cabal complete eradication of all use of natural substances like (but not limitted to) Vitamin D3. This works better than vaccines and produces none of the seconary effects and chronic health problems which their methods and strategies foist on us. If they get anything to start toward total Single Payer they will make all alternative, integrative, complementary, natural and informational resource for them disappear. They will control research and investigation to only those therapies that will support their (presently obsolete) approaches to health theory, diagnosis, testing, care and recuperation. If you think what they do is expensive now, well, what do you think it will be like when you have absolutely no recourse except a different provider who can only give you more of the same – by law?
      If you are that much of a reflex knee jerk, think-inside-the-box, welfare brain then, please, find someone in your community who can teach you about health – like a chiropractor, health foods store owner, nutritionist (not a dietitian) or natural health professional. Then decide if you think Government health control is a good idea or not.
      What is ore beneficial for you? You can learn to take responsibility for keeping yourself strong and healthy. Or, you can surrender decisions and control to businessmen who only make money if you are sick.

  • It looks like the drug companies and mainstream medicine has again successfully covered up very good news regarding very cost effective food supplements – in this case vitamin D3. Supplements could reduce health costs dramatically if they were fully used, which they have not been, even at this late date.

  • Please let the government know that we are aware of the deliberate atrocities done daily that are taking our sun also. Areal spraying of unsuspecting people is against the law and against the Constitution of the United States of America. This is an attack on all life! This must stop!

  • Vitamin D3 is the key and the last D3 I bought had soybean oil and I was outrageed. What a waste! Soy prevents the absorbtion of most vital nutrients. Just talking or writing about Vitamin D just doesn’t cut it. People need info about the Sunlight Vitamin D. Sunlight at mid day for 10 to 20 minutes with out sunscreen is a good idea. No sun?? Supplement with D3.

  • Robert Hardeman

    I know since seeing a nutripath “instead of my reg doctor” i feel much better, and i do have several health problems includeing emphazima, and use to get sick ALOT!!!! but since going to him, i havent been sick in several months now, and he has me on Vitamin D-3 and it seems to be helping me alot, and i am so glad i went to see him…

  • Janet Bogart

    My vitamin D level has been moving lower (from 25 to 11!!) after many months of taking 50,000 iu weekly and 1200-1800 units daily. The doctors are doing the right thing but I am not responding properly. Any ideas? I doubt I will receive a reponse but don’t know where to turn with my questions.

    • Meri Withrow

      Hi Janet, I was having the same problem with vitamin D. I have been working with a couple of things such as quiet meditation, really slowing my heart and adrenals down and taking suppliments to calm the adrenals. My sense is that this occurs in those of us that are always taking care of others and or working constantly without stopping to listen to our own heart and our needs. Whatever inspires and heals you and your body specifically. Sincerely, Meri

    • Jeff Evanoff

      Hi Janet
      Make sure that you are taking D3 and not the D2. Also make sure that you take it with fat and take it along with all your other fat soluble vitamins. It is important for all of us to get our digestive systems healthy in order to absorb all of the good nutrition that you hopefully are taking in. Work with your doctor and continue to have your levels checked. I take mine in the early morning and this has been working well for me these last 3 years. Good luck!
      Sincerely, Jeff

  • William E. Hudson

    I am happy that there are organizations springing up that are working for increased knowledge and participation in natural health practices. If we want to improve our health and, at the same time, reduce the cost of maintaiing good health, we need to use as many natural cures as possible. I have used natural cures for over twenty years, and I have found that my health is better–and the cost of maintaining good health has been DRASTICALLY reduced. If I feel a cold or flu coming on, I use a combination of fresh Garlic and Colloidal Silver–and if it’s the Flu, I add the AHCC mushroom complex. I can’t remember the last time I had a cold or flu that lasted more than 48 to 72 hours (and if I catch it early it’s gone even sooner). And with the new emphasis on Vitamin D, I’m taking it every day, along with a routine of natural vitamins, herbs and other natural cures. Does our government have any idea how much they could cut from our health bills with a more widespread use of natural remedies?And of course the good thing is that we would all feel much better. Thanks for listening–William Eugene Hudson ([email protected])

  • THANKS FOR GETTING THE WORD OUT AND PETITIONING THESE AGENCIES TO PAY ATTENTION—ONLY THIS KIND OF GRASS ROOTS FOCUS USING REAL SCIENCE, THAT IS READILY AVAILABLE TO THESE AGENCIES BUT WHICH THEY CHOOSE TO IGNORE IN FAVOR OF BIG PHARMA, IS GOING TO BRING ABOUT THE CHANGE WE NEED TO SEE IN HEALTH CARE—NOT MORE ACCESS TO A SEVERELY DYSFUNCTIONAL SYSTEM. IT WILL COME FROM THE BOTTOM UP NOT THE TOP DOWN. THANK YOU FOR YOUR INTELLEGENCE, YOUR PASSION AND YOUR RESOLVE TO BRING POSITIVE CHANGE. I HOPE YOU DO MORE PETITIONS TO CONGRESS, GOVT HEALTH CARE AGENCIES ETC. I AM HAPPY TO SIGN THEM AS THIS IS ONE OF THE FEW WAYS I CAN MAKE MY VOICE HEARD TO THE LARGER SYSTEM. I DO IT DAILY IN MY WORK AS A FUNCTIONAL MEDICINE NURSE PRACTITIONER ONE ON ONE WITH MY PATIENTS. UNFORTUNATELY EVEN NURSE PRACTITIONER ORGANIZATIONS ARE SIMPLY SUPPORTING A VERY BROKEN SYSTEM, AND NOT MAKING USE OF THE TONS OF INFORMATION OUT THERE ABOUT HOLISTIC, NATURAL, INTEGRATIVE, FUNCTIONAL MEDICINE.

  • Knut Hjeltnes

    This isthe first year that I have been taking Vit. D – in addition to the Multi-Vit. I usually take – and I have had less frequent and less severe colds and flues. in addition to the Vit.D supplementation I take 800mg Ibuprofen twicw a day for a few days if I have been infected, and this really shortens and reduces the infection dramatically. This sounds almost too simple, but I believe is a much better for you than heavy antibiotic treatments every time you have an infection.

  • Stop taking D3 in pill form! “Vitamin” D is produced in abundance by our body as a reaction to exposure to UVB of sunlight.
    Even “progressive” doctors are being far too careful in informing patients about the true amounts of D that is necessary. In the last century we have come to accept 400 IU’s as sufficient but in fact that amount only reflected the needs of the bare minimum that small children needed only for protection against rickets.
    In recent research it has been discovered that a vast number of cell and organ systems have D receptors and the need for D is far more closely associated to what we would get from an amount of time in sunlight (or a home unit sun bed) and that is at least 20,000 IU’s in a 20 minute exposure.
    Why would our bodies evolve with the ability to produce so much D if it wasn’t needed?
    In regards to our natural immune system, when we continue to use foreign bodies to supplant the work on nature, our bodies lose the ability to produce that which is being artificially supplied. As well, unlike nature, there is a very real toxicity level in D consumption that does not exist in our bodies with natural sunlight exposure.
    Our western system of “Health Care” is just so badly named! The medical and pharmaceutical industries are not interested in our “Health Care” because they can’t make money from healthy people. In western society we have “sickness care” the industries are geared to produce medicine and treatment to combat the actual sickness rather than trying to keep the populous from getting sick in the first place!
    Whatever your beliefs, neither G-d or mother nature would have created us or allowed us to evolve naked under the sunlight, without sunscreen, if it was going to kill us.

  • Sunbridge Tanning

    Re: petition
    This is all fine and good but the problem remains: government serves those with the biggest wallet. Unless this industry can compete with the big pharma lobby and their wealth the point is moot. We also face the task of undoing the conditioning of the intentionally dumbed-down, flouridated and radiated public who have chosen to believe the lies put out by corrupt organizations as those listed by you, Bill. I don’t believe that the majority of shop owners are in a position to engage in such an endeavour and especially when many are struggling to keep their doors open in this abysmal economy. So, we need to examine much more aggressive solutions. Perish the thought but perhaps we seriously consider playing by THEIR ‘rules’?

  • Life Extension Foundation offers great scientific information! They have recently provided good evidence that most people should supplement with at least 5,000 IU of Vit D daily to help prevent many serious conditions.

  • Andy

    For Janet Bogart: A few thoughts regarding the dropping vitamin d levels. You may have a fat malabsorption issue or be taking medications that interfere with fat absorption. Vitamin d as a fat soluble vitamin would not be absorbed well in these cases. Additionally you may try an alternative source for your vit d supplements such as http://www.bio-tech-pharm.com as this is a FDA regulated facility with 50,000 IU capsules of D3. If fat malabsorption were the case UVB treatment – as with tanning beds during the winter or the sun in warmer months – would work fine to raise 25-OH vit d levels. Of course discuss this with your doctor and avoid sunburns if you choose this. If you have fat malabsorption you are probably deficient in other nutrients as well and this would need to be evaluated.

  • “there were 50% fewer respiratory infections and 300% fewer days of absence.”
    300% fewer is impossible. If some have 9 days of absence how can others have 9 minus 27 days of absence? I’m guessing you meant 2/3 fewer or 67% fewer or 3 days of absence.

  • @ Janet Bogart
    Maybe your doctors have supplied ERGOCALCIFEROL 50,000iu Vitamin D2.
    This is the form animals use humans evolved to function best with D3.
    There are many people who do not absorb or metabolize this form of vitamin d2.
    Also D2 speeds up the rate of catabolism of vitamin D so compared with using D3 ergocalciferol has a far shorter useful lifespan (that’s assuming it’s absorbed and hydroxylated)
    As light degrades vitamin D it’s possible the capsules you are taking may have been exposed to light at some point.
    I prefer to take 10,000iu/daily either in MCT oil or olive oil. You can easily buy 5000iu/D3 in MCT from the usual online discount providers.

Leave a Reply

Your email address will not be published. Required fields are marked *

Related Posts